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Thus, the impaired urease and redox activities and low extracellular pH of gsh2 mutants likely contributed to the lack of melanin in these mutants (Fig

This was followed by glucose-6-phosphate dehydrogenase (G6PD), a protein crucial for the pentose phosphate pathway (PPP), followed by several proteins essential for ECM remodeling such as integrin alpha-2 (ITGA2), integrin alpha-V (ITGAV), integrin alpha-1 (ITGA1), filamin-A (FLNA1) and transforming growth factor induced protein [TGFBI, also known as ig-H3 (Table 1)]